Digestive Disorders news and health articles
Friday 10 October, 2008
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Digestive Disorders news and health articles
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| 10/10/2008 07:35 AM | ||
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| 10/10/2008 03:13 PM | ||
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| 10/10/2008 06:00 AM |
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Shire Limited, the global specialty biopharmaceutical company, announces that data published in Gut show that 64.4% of patients with mild to moderate ulcerative colitis (UC) who achieved clinical and endoscopic remission maintained this at 12 months when given two mesalazine 1200mg gastro-resistant, prolonged release tablets (Mezavant XL) once a day as a maintenance therapy.
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| 10/10/2008 05:00 AM |
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The Ministry of Health and Long-Term Care's listeriosis update as of Monday, October 8, 2008. Total number of cases - 44 Total confirmed cases - 40 Total cases under investigation - 4 Number of deaths among confirmed cases - 22 Number of death where listeriosis was an underlying or contributing cause - 15 Number of death where cause is undetermined - 7 "It's clear now that the worst of the outbreak is over," said Dr.
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| 10/09/2008 07:00 AM |
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A 30 percent increase in chronic kidney disease over the past decade has prompted the U.S. Renal Data System (USRDS) to issue for the first time a separate report documenting the magnitude of the disease, which affects an estimated 27 million Americans and accounts for more than 24 percent of Medicare costs. The USRDS is funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of Health (NIH).
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| 10/09/2008 05:00 AM |
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Based on results of a landmark study, researchers at Mayo Clinic's Florida campus see a future in which virtual biopsies will eliminate the need to remove colon polyps that are not cancerous or will not morph into the disease.
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| 10/08/2008 12:00 PM |
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There is no evidence probiotics can relieve the symptoms of eczema, but there is some evidence that they may occasionally cause infections and gut problems. These findings from The Cochrane Library come at a time when use of probiotics to treat eczema is increasing. Eczema is an itchy skin condition that affects more than 1 in 20 people at some time in their lives and is especially common in children.
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| 10/08/2008 12:00 PM |
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The research team led by Levent Erdem from Sisli Etfal Teaching and Research Hospital of Turkey investigated the prevalence and demography of microscopic colitis in patients with diarrhea of unknown etiology and normal colonoscopy in Turkey. This was published in the World Journal of Gastroenterology.
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| 10/08/2008 12:00 PM |
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Hepatic ischemia-reperfusion injury is a serious complication but unavoidable problem in liver surgery including liver transplantation and hepatic resection. The most important consequence of this pathological process is multiple organ failure with a high mortality rate.
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| 10/08/2008 12:00 PM |
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Cancer immune surveillance is considered to be important in the anti-tumor protection of the host. The growing tumor escapes the immune control under the immunosuppressive conditions. The surgical removal of the tumor may reverse the immunosuppression. The TF antigen and Tn belong to tumor-associated carbohydrate antigens (TACA). TF antigen is implicated in the metastatic spread due to the adhesion of cancer cells to the endothelium.
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| 10/08/2008 10:00 AM |
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Salix Pharmaceuticals, Ltd. (NASDAQ: SLXP) today announced that 1.5 g mesalamine granules once-daily maintained remission versus placebo in ulcerative colitis (UC) patients who switched from another 5-ASA product (78 percent of relapse-free subjects vs. 59 percent [P
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| 10/08/2008 09:00 AM |
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Biothera announced today that it completed enrollment in the first arm of its metastatic colorectal cancer (mCRC) trial in July. The dual-arm trial is evaluating the combination therapy of Imprime PGG®, the company's lead drug candidate, and Erbitux® (cetuximab), a monoclonal antibody from ImClone Systems, with or without chemotherapy.
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| 10/08/2008 08:00 AM |
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A simulated gastrointestinal system is helping scientists test contaminated soil for its potential to harm humans. The method is likely to save time and money for people hoping to repurpose land with an industrial past. Most testing for potential arsenic exposure is conducted in recognition of a dirty little secret of modern life: Humans unknowingly eat a little bit of soil each day.
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| 10/08/2008 04:00 AM |
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The Institute for OneWorld Health (iOWH), the US-based non-profit pharmaceutical company that develops drugs for people with infectious diseases in the developing world, announced that a delegation of US experts in diarrheal disease is meeting in the UK from October 6-9, 2008.
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| 10/08/2008 04:00 AM |
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Given Imaging Ltd. (NASDAQ: GIVN) today announced data from a pilot study that demonstrate the Company's PillCam® capsule endoscopy of the esophagus can significantly reduce health care costs in a prison population through on-site evaluation of esophageal varices in cirrhotic patients.
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| 10/08/2008 02:00 AM |
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Alba Therapeutics Corporation presented results from two clinical studies this week at the American College of Gastroenterology (ACG) 2008 Annual Scientific Meeting.
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| 10/08/2008 02:00 AM |
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Ardea Biosciences, Inc. (Nasdaq: RDEA) announced that a poster entitled "RDEA119, a Potent and Highly Selective MEK1/2 Inhibitor is Beneficial in Dextran Sulfate Sodium (DSS) -- induced Chronic Colitis in Mice," was presented at the American College of Gastroenterology (ACG) 2008 Annual Meeting in Orlando, Florida.
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| 10/07/2008 12:00 PM |
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Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company, announced the results from a multidisciplinary analysis of in vitro and in vivo data of LIALDA® (mesalamine) versus Asacol® (mesalamine) that investigated factors including transit and disintegration of tablets along with tablet coating thickness that may affect a consistent release of 5-aminosalicylate acid (5-ASA) in both therapies.
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| 10/07/2008 11:00 AM |
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The Johns Hopkins University School of Medicine and the American Academy of Nurse Practitioners (AANP) today announced the launch of the Performance Improvement component of the Educational Initiative on Constipation (EIC) at the Collective Clinical Forum: EIC, a satellite symposium that took place during the American College of Gastroenterology (ACG) annual meeting on October 5, 2008, in Orlando, Fla.
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| 10/07/2008 10:00 AM |
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Endoscopic therapy is emerging as an alternative to surgery in patients with esophageal cancer given the low likelihood of spread to the lymph nodes. New research presented at the American College of Gastroenterology's 73rd Annual Scientific Meeting in Orlando evaluated the long-term efficacy of endoscopic mucosal resection, or EMR, in the treatment of patients with early stage esophageal cancer or Barrett's esophagus.
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| 10/07/2008 10:00 AM |
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While smoking poses a health threat to both men and women, women require less tobacco exposure than men to have a significant increased risk for colorectal cancer, according to new research presented at the 73rd Annual ACG Scientific Meeting in Orlando. In a separate analysis, researchers found smoking may increase the risk of pancreatic cancer precursor lesions, particularly in patients with a strong family history of the disease.
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| 10/07/2008 10:00 AM |
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Most people who experience chronic heartburn have symptoms that are caused by gastroesophageal reflux disease, or GERD. Two new studies presented at the 73rd Annual Scientific Meeting of the American College of Gastroenterology examined eosinophilic esophagitis (EoE), a condition that can mimic symptoms of GERD, in a small proportion of people. The first study found that the diagnosis of EoE, previously termed "allergic esophagitis," peaked during the summer months.
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| 10/07/2008 09:00 AM |
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With a long-held commitment to continuously improving the quality and safety of patient care, Mayo Clinic researchers are recommending a new technologically-advanced labeling system aimed at reducing specimen labeling errors in a high-volume gastrointestinal endoscopy center. That conclusion is based on the results of a study they are presenting at the 2008 American College of Gastroenterology (ACG) Annual Meeting.
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| 10/07/2008 09:00 AM |
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A study released at the 73rd Annual Scientific Meeting of the American College of Gastroenterology in Orlando found that a new therapeutic treatment, when delivered endoscopically and used in combination with chemotherapy and radiation therapy, improved survival rates in patients with locally advanced esophageal cancer. Cancer of the esophagus often has a poor survival rate. Dr.
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| 10/07/2008 07:00 AM |
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A research study funded by JDRF suggests that a common intestinal bacteria may provide some protection from developing type 1 diabetes. The findings provide an important step towards understanding how and why type 1 diabetes develops in people, and may lead to potential cures.
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| 10/07/2008 06:00 AM |
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Results of a survey presented at the American College of Gastroenterology's 73rd Annual Scientific Meeting in Orlando revealed that many parents do not accurately perceive their children as overweight or at risk for adulthood obesity. Obesity in the United States is often accompanied by an increased risk of gastrointestinal diseases and has emerged as a major health concern, particularly the issue of obesity among children and adolescents. Researcher Rona L. Levy, Ph.D.
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| 10/07/2008 06:00 AM |
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Researchers offer provocative new theory for common cause of surgery Could there be a link between high levels of air pollution and the risk of appendicitis? New research presented at the 73rd Annual Scientific Meeting of the American College of Gastroenterology in Orlando, suggests a novel connection. "Adult onset appendicitis is a common condition whose cause is unclear and almost universally requires surgery," explained Dr. Gilaad G.
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| 10/10/2008 06:00 AM |
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Shire Limited, the global specialty biopharmaceutical company, announces that data published in Gut show that 64.4% of patients with mild to moderate ulcerative colitis (UC) who achieved clinical and endoscopic remission maintained this at 12 months when given two mesalazine 1200mg gastro-resistant, prolonged release tablets (Mezavant XL) once a day as a maintenance therapy.
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| 10/08/2008 10:00 AM |
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Salix Pharmaceuticals, Ltd. (NASDAQ: SLXP) today announced that 1.5 g mesalamine granules once-daily maintained remission versus placebo in ulcerative colitis (UC) patients who switched from another 5-ASA product (78 percent of relapse-free subjects vs. 59 percent [P
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| 10/08/2008 02:00 AM |
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Ironwood Pharmaceuticals, Inc. (formerly Microbia, Inc.) and Forest Laboratories, Inc. (NYSE: FRX) announced the presentation of results from a Phase 2b study assessing linaclotide's safety and efficacy in 420 patients with irritable bowel syndrome with constipation (IBS-C).
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| 10/07/2008 11:00 AM |
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The Johns Hopkins University School of Medicine and the American Academy of Nurse Practitioners (AANP) today announced the launch of the Performance Improvement component of the Educational Initiative on Constipation (EIC) at the Collective Clinical Forum: EIC, a satellite symposium that took place during the American College of Gastroenterology (ACG) annual meeting on October 5, 2008, in Orlando, Fla.
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| 10/07/2008 10:00 AM |
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Several studies presented at the American College of Gastroenterology's 73rd Annual Scientific Meeting in Orlando highlight the safety and efficacy of probiotics in improving symptoms and normalizing bowel movement frequency in patients suffering from constipation or diarrhea related to Irritable Bowel Syndrome (IBS).
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| 10/07/2008 10:00 AM |
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Vitamin D replacement may be necessary to reverse deficiency-related bone loss New research presented at the 73rd Annual Scientific Meeting of the American College of Gastroenterology in Orlando found patients with inflammatory bowel disease or chronic liver disease were at increased risk of developing Vitamin D deficiencies. Two separate studies highlight the importance of regular Vitamin D checkups in the evaluation of patients with certain digestive diseases.
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| 10/07/2008 02:00 AM |
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Ironwood Pharmaceuticals (formerly Microbia) announced presentation of data from a pair of preclinical studies delineating the role that cyclic guanosine monophosphate (cGMP) plays in alleviating intestinal pain. These studies demonstrate that cGMP inhibits intestinal pain in a preclinical model of intestinal hyperalgesia and desensitizes colonic afferent nerves in a similar model of experimental colitis.
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| 10/07/2008 02:00 AM |
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New research on the benefits of probiotics in children and seniors was presented at The American College of Nutrition (ACN) Annual Meeting in a symposium, "Practical Applications of Probiotics in Health and Disease." Scientific experts in the fields of pediatrics, aging, and nutrition discussed the potential uses for probiotics in children as well as the elderly, and for health conditions such as Inflammatory Bowel Disease (IBD).
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| 10/06/2008 11:00 AM |
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Salix Pharmaceuticals, Ltd. (NASDAQ:SLXP) today announced findings from two analyses of a Phase II clinical trial that demonstrate the utility of rifaximin, a non-absorbed, gut-selective antibiotic, in the treatment of patients with diarrhea-predominant irritable bowel syndrome (IBS).
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| 10/06/2008 02:00 AM |
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Scientists report online in Nature that they have linked the health of specialized gut immune cells to a gene associated with Crohn's disease, an often debilitating and increasingly prevalent inflammatory bowel disorder. The link to immune cells intrigued researchers at Washington University School of Medicine in St. Louis because they and others believe Crohn's disease is caused by misdirected immune responses in the intestine that damage gut tissue.
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| 10/03/2008 03:00 AM |
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Ore Pharmaceuticals Inc. (NASDAQ: ORXE) announced today that it has initiated dosing subjects with GL1001, the Company's lead drug candidate, in a multiple ascending dose clinical trial. GL1001, the first clinical-stage inhibitor of the ACE2 enzyme, is an orally administered small molecule that has decreased several disease activity measures in in vivo models of inflammatory bowel disease (IBD) and gastritis.
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| 09/27/2008 02:00 AM |
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Ironwood Pharmaceuticals (formerly Microbia) and Forest Laboratories, Inc. (NYSE: FRX) announced they will present results of a Phase 2b study investigating linaclotide's safety and efficacy in 419 patients with irritable bowel syndrome with constipation (IBS-C) in a plenary session at the American College of Gastroenterology (ACG) 2008 Annual Scientific Meeting in Orlando, Fla. on October 7, 2008.
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| 09/26/2008 08:00 AM |
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The Johns Hopkins University School of Medicine, Office of Continuing Medical Education (JHU) and the American Academy of Nurse Practitioners (AANP) announced today the launch of the Educational Initiative on Constipation (EIC) Award for Clinical Excellence (ACETM) program.
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| 09/19/2008 09:00 AM |
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Patients with IBD have high risk of infection by hepatitis viruses B or C because during the course of their disease, they need blood transfusions, and sometimes surgical and endoscopic procedures for diagnosis and treatment. It is important to alert health professionals about prevention and early diagnosis of HBV infection because the steroids and immunosuppressant drugs used in IBD treatment worsen the HBV liver disease.
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| 09/19/2008 08:00 AM |
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The National Institute for Health Research Health Technology Assessment (NIHR HTA) programme has funded a £1.6 million clinical trial to compare two powerful drugs for people with steroid resistant acute severe ulcerative colitis (UC). UC affects approximately 150,000 people in the UK and is a major burden on patients and NHS resources, as it often leads to severe morbidity, grossly impaired quality of life, frequent and long inpatients stays and emergency colectomy.
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| 09/12/2008 04:00 AM |
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SIBO is a common feature in IBS and in fact may be directly related to the genesis of IBS symptoms. An ERBHAL on a lactulose breath test may indicate SIBO. Antibiotics and elemental diets have been shown to be effective in treating SIBO, but the efficacy of probiotics is untested. A pilot study was undertaken to determine the effect of L. strain Shirota (Yakult(R)) on intestinal fermentation patterns of IBS patients.
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| 09/11/2008 05:00 AM |
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Around 14 million people in the UK have a bladder control problem and 6.5 million a bowel control problem - that's more people than those suffering with Asthma, Diabetes and Epilepsy put together. One in ten ladies are also likely to suffer incontinence in their later years. Yet incontinency is a condition that many people are too embarrassed to discuss and seek help for.
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| 09/10/2008 05:00 AM |
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Boston University School of Medicine (BUSM) will present The Seventh Annual Sue Kim Hanson Lecture in Immunology on Friday, September 12, 2008 at noon in the School's Keefer Auditorium. The annual lecture is in honor of Sue Kim Hanson, MA, PhD '02, a former researcher in BUSM's Pulmonary Center. Kim Hanson, along with her husband and daughter, were passengers on United Airline flight 175, the second plane that struck the World Trade Center on September 11, 2001.
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| 09/05/2008 05:00 AM |
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Alte Bioscience, Inc., a development stage pharmaceutical company, is pleased to announce the filing of a provisional patent for a new class of drugs that may benefit patients with inflammatory bowel disease. This is the latest in a series of pharmaceutical inventions held by Alte Biosciences, adding to its portfolio of patents of drugs for the treatment of late onset depression and innovative systems for drug delivery, packaging, and manufacturing.
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| 09/01/2008 04:00 AM |
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Researchers have discovered two new genes that increase the risk of developing inflammatory bowel disease (IBD) in childhood. While further study is needed to identify the specific disease-causing mutations in these new genes, the researchers say the genes are particularly strong candidates to be added to the list of genes already known to affect IBD.
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| 08/27/2008 10:00 AM |
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A new study published in the August 27 issue of JAMA reports good news for men who enjoy nuts, corn, or popcorn. Researchers studying a large cohort of men have found that consumption of these foods does not increase the risk of diverticulosis or diverticular complications - a conclusion that is contrary to common beliefs. Diverticular disease is characterized by having diverticula in the colon, and it often leads to diverticulitis and diverticular bleeding.
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| 08/01/2008 02:00 AM |
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Two new review articles that cover therapeutic approaches to irritable bowel syndrome (IBS) in the July issue of Nutrition in Clinical Practice, cite growing evidence that probiotics, and specifically Bifidobacterium infantis 35624 (Bifantis®), are effective in helping manage IBS. Both articles point to data that suggest Bifantis (available in the U.S.
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| 07/23/2008 03:00 AM |
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Anadis Ltd (ASX:ANX; OTC:ANDIY), a biopharmaceutical company focused on research, development and production of immune milk (colostrum)-derived polyclonal antibodies and other proteins to address major diseases, today announces the initiation of a clinical trial with top clinical scientists at Tel Aviv Sourasky Medical Center in Israel.
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| 07/16/2008 09:00 AM |
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Physician-scientists from NewYork-Presbyterian/Weill Cornell, involved in clinical trials for a new drug for those who suffer from inflammatory bowel disease (IBD), say it is the best option among available drugs. Gaizo is a reformulation of the active ingredient 5-ASA in currently available drugs. However, the researchers found that 99 percent of the active ingredient in the new pill is released in the colon compared to only 70 percent in other common IBD drugs. Dr.
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| 07/16/2008 08:00 AM |
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Stem cells are being studied at NewYork-Presbyterian/Weill Cornell to heal the gut in subjects suffering from Crohn's disease. Physician-scientists believe that these cells might help to restore the ability of the immune system to control inflammation by secreting anti-inflammatory proteins into the digestive tract, allowing for regeneration of tissue and prevention of scar tissue.
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Additional Health Resources
International Food Information Council
Nutrition Information Bulletin Board & Learning Experience (NIBBLE)
Diet-Plan Diagnosis: Is Yours Healthy and Safe? (Nemours Foundation)
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